Skip to main content

In our previous post, we discussed CBD Oil Drug Interactions: What Should We Know? More and more people are interested in using CBD as a complementary treatment for many health problems. The same goes for pets. We want them to be healthy and happy and that’s why CBD is a great option. Dog CBD drug interactions are very similar to human medication. In this article, we talk about this in more detail.

Natural Foods: Inhibitors and Inducers

Very similar to humans, our pets metabolize medication in the liver and mostly with the help of special enzymes P450. These enzymes are very important as they can easily break down all the extra chemicals that drugs through in the blood and safely remove it from the body.

An interesting fact that some foods in combination with medication can inhibit or induce our enzymes.

According to this Wikipedia list, such foods as broccoli, cauliflower, brussel sprouts or even chargrilled meat act as inducers when interacting with certain medication. And foods like grapefruit, turmeric, cumin, echinacea, herbal teas and coffee act as inhibitors of enzymes and increase drug effects on the body.

CBD products like oil and other supplements act in the same way as it also natural and plant-based. Moreover, in proper combination, CBD can act as an inhibitor and an inducer as well!

With our human bodies everything is clear, if we have discomfort, we can ask advice or go to a doctor. But our pets can’t talk, and they trust us with whatever we feed them. Let’s see how CBD can act in certain drug combinations and how that helps to understand our pets better.

Dog CBD Oil Drug Interaction Tips

We know CBD is very safe to use on its own and the only side effect you can experience if you take to much is an upset stomach. But let’s see what happens when your pet has a specific health condition.


Many clinical trials proved that CBD reduces seizure frequency in dogs and cats. And even more effective if given with traditional anti-seizure meds like clobazam or phenobarbital. Basically, you can adjust the dosage. Reduce the dosage of traditional medication with many nasty side effects and increase CBD dosage. That works effectively with minimum side effects for your dog.


Painkillers commonly prescribed for injured, aging and chronically ill pets. Carprofen, gabapentin, meloxicam and etodolac are the most popular NSAIDs used for pets. We know that side effects are not great and can lead to liver failure, upset GI and compromised immune system.

Even though CBD is a great pain reliever on it’s own, it also can increase the effect of painkillers. Which gives an opportunity to significantly reduce regular NSAID dosage and use natural oil as a main treatment in the routine. As a result, fewer side effects and more actual pain relief.


CBD oil drug interaction is very important when it comes to cancer. CBD is a well-known product to use in oncology and has great anti-tumor properties. It helps relieve really bad side effects of chemotherapy such as anemia, pain and nausea.

In addition, many kinds of research shows that CBD enhances the effects of chemo and fights cancer more efficiently! Of course, you want to consult your doctor on how you can adjust CBD dosage so it will benefit the cancer treatment of your dog.


Usually such medication as Xanax, Amitriptyline, Ativan, Paxil, Zoloft and many others, vets are prescribing for dogs with anxiety, phobias and depression. On the other side, such meds like Xanax can be addictive and provoke bad side effects like dizziness, drowsiness, diarrhea, vomiting and even blurred vision.

CBD oil drug interactions might increase some of the side effects. That’s why dosage is key. You can use CBD oil for pets to improve bad side effects and decrease current medication dosage. Naturally, CBD will increase the effectiveness of minimum dosage but with less side effects!

CBD is A Safe And Natural Way to Help Your Pet!

We get a lot of questions about using CBD to replace prescription or OTC medications. Most medications can be entirely replaced with CBD, or dramatically reduced while being used in cohesion with CBD. Pawt4Paws CBD is a pure isolate CBD oil that exclusively contains hemp CBD. We test our oil with a 3rd party to ensure that there is virtually no THC and no harmful pesticides. Your pet’s safety is our number priority.

Pawt4Paws was started for a dog with seizures, and we always go back to wanting the best we can possibly give to you and your fur family!

Consult With Your Vet

To know for sure how strong dog CBD oil drug interaction is, it is best to consult with your vet. It’s good to keep in mind that some drug interactions are not always a bad thing. There is a great chance that your CBD oil can be an unexpectedly amazing solution in dog treatment. Our pets safety and well being is always our top priority, please consult with your vet and make your vet is aware that you are using CBD!